Since 1998 · Zagreb & Daruvar

Scalp Mesotherapy in Croatia

Hair that has thinned, lost density, and keeps ending up on the brush is usually first fought with shampoos and vitamins. Scalp mesotherapy delivers nutrients directly into the skin of the scalp, where the follicle does its work. Before we suggest a single treatment, a scalp analysis shows whether mesotherapy would help you at all — because for some people it will not.

Ana Maletić, MD, PhD, at Polyclinic Maletić

Mesotherapy is usually the entry treatment for the scalp — the one people think of at the first signs, while the hair has not yet visibly thinned. That is exactly why we measure the scalp first, and only then agree on a series of treatments.

Is this for me?

What scalp mesotherapy is and what is actually injected

Scalp mesotherapy is the delivery of a preparation of nutrients directly into the skin of the scalp, with very fine needles and at shallow depths. The goal is for the substances to reach the layer where the follicle works, instead of staying on the surface or passing through the whole body.

This is a medical procedure, not a cosmetic treatment. That means an examination comes first, and the composition of the preparation is set for each patient individually, not according to a preset scheme.

What goes into the preparation

Preparations for scalp mesotherapy most often contain vitamins, minerals, amino acids, and other substances that support the work of the follicle and the condition of the scalp skin. With us, the composition and amount are put together individually, based on your findings — so two patients of the same age with similar hair will not necessarily receive the same mix.

Mesotherapy improves the conditions in which hair grows, but it does not change the reason the hair started falling out.

Why an injection, and not a shampoo or a pill

Most people come to us after several months of ampoules, shampoos, and supplements. The problem with that route is not the ingredients but getting them to where they need to be. Applying them into the skin of the scalp achieves higher local availability of the substances with less exposure for the rest of the body — which is the basis of the method.

That also explains why mesotherapy cannot replace treating the cause. If the body lacks iron or the thyroid is not working as it should, that finding is treated with medication, not with an injection into the scalp.

The right indication

Who benefits most from scalp mesotherapy

The people who benefit most are those who come while the change is still in its first signs. When the hair has started to thin but the follicles are still alive and active, the therapy has something to work with. The further the process has advanced, the less it is reasonable to expect from it.

Situations in which we suggest it

Weakened and damaged hair — a thin hair shaft that breaks easily and struggles to hold a style.
Early-stage hair loss — when density is dropping and the part line is slowly widening.
Hair loss after childbirth, illness, or a longer period of stress — when the condition has settled but recovery is not coming.
Preserving hair quality — in people whose process is known and predictable, where the goal is to slow it down.
Maintaining the results of other scalp therapies — when the state that has been achieved needs to be kept.

Mesotherapy, PRP, or polynucleotides — what decides

That question comes up at almost every consultation, because all three therapies target the same scalp condition. They differ in what is applied. A PRP treatment uses your own plasma, polynucleotides are a purified preparation with a regenerative effect, and mesotherapy delivers nutrients composed according to your findings.

The decision is not made by a treatment’s popularity but by what is measured on the scalp. Combining two therapies is common, because the same scalp can need both nutrition and regeneration at the same time.

“Mesotherapy nourishes the scalp and can improve hair quality, but it does not stop hereditary hair loss. If someone comes in with advanced androgenetic alopecia, six treatments will not change what brought them in — and it is better they hear that before they start.” — Ana Maletić, MD, PhD

How it is performed

What a scalp mesotherapy treatment with us looks like

The whole procedure takes about half an hour and is a minimally invasive medical procedure.

Duration: about 30 minutes
Anesthesia: usually not needed
Protocol: most often a series of 6 treatments; the schedule is set by your findings
Performed by: Ana Maletić, MD, PhD

1 · Examination and scalp analysis. We measure the scalp with the TrichoLAB system. The examination is non-invasive and painless, and it records hair shaft thickness, density, and the number of hairs per follicular unit, separately by region. From those numbers we can see what kind of hair loss is involved and whether mesotherapy has anything to work with.

2 · Preparing the mix and the scalp. The composition is set by your findings, and the scalp is disinfected following medical protocol.

3 · Application. We apply the preparation with very fine needles, in a series of points across the area we have mapped out. Anesthesia is usually not needed.

4 · After the treatment. You return to your obligations right away, with no downtime. You receive written instructions for the next two days, because saunas, pools, and harsher hair care are avoided in that period.

The treatment is most often done in a series of six, and after the series we measure the scalp again and compare it with the initial findings. Progress is checked by measurement, not by memory of how the hair used to look.

See the full price list

Honest about the limits

The limits of scalp mesotherapy

The method has four limitations you should know before agreeing to a series.

It does not stop hereditary hair loss. Mesotherapy is not an approved treatment for androgenetic alopecia. It can support the scalp, but it does not change a genetically driven process.

It does not create new follicles. Where a follicle is gone, no preparation brings it back. In that situation, a conversation about a hair transplant is more honest than a series of treatments.

The evidence is weaker than the ads suggest. Published literature reviews show that studies exist and the results are mostly favorable, but the samples are small, the quality of the studies is modest, and there is no standardized preparation or protocol. Results are better when mesotherapy is combined with other therapies than when it stands alone.

Side effects exist, although they are rare. Most are mild and transient: redness, sensitivity, itching, swelling, or a small bruise. Rarer events are described in the literature — folliculitis and, very rarely, an inflammatory reaction and paradoxical increased hair shedding. That is why a physician performs the treatment, and why an examination comes first.

If your findings show that mesotherapy would change nothing for you, you will hear that at the first examination, together with a proposal that has support in the findings. A series of six treatments takes both time and money, so we suggest it only when there is a reason for it.

After the series

What the result looks like after six treatments

The result is not assessed on the day of the last treatment. In published studies of scalp mesotherapy, measurement is repeated several weeks after the series ends, and the change is looked for in hair count, density, and hair shaft thickness — the parameters trichoscopy records before the eye notices them. Because the hair growth cycle lasts months, the final picture comes together over that period, not within the series. Mesotherapy does not stop the course of hereditary hair loss, so even a good finding does not mean the scalp is no longer monitored. In some patients the change shows first in the small things: less hair stays on the brush after washing, and the hairstyle no longer has to be arranged so that something is covered.

Why us

Why choose us for scalp mesotherapy

ABHRS Diplomate

Dr. Ana Maletić is the only physician in Croatia with this title, one of 260 physicians worldwide

Croatia’s only ISHRS member

regular membership in the International Society of Hair Restoration Surgery

One of 6 clinics worldwide

with this level of international certification for hair treatments

The only clinic in Croatia with all four methods

FUE, DHI, Sapphire, and STRIP — we choose the method based on your findings, not on what we happen to offer

Since 1996

the year hair transplant training began at Polyclinic Maletić

TrichoLab scalp analysis

hair shaft thickness, density, and hairs per follicular unit measured before every plan

An individually composed preparation

the composition and amount are set by your scalp findings, not by a ready-made package

We also tell you when therapy makes no sense

if your findings show mesotherapy would change nothing for you, we will tell you so

Book a discreet consultation

Who we are

Who will be taking care of you

The Hair Center is led by Ana Maletić, MD, PhD, a specialist in plastic, reconstructive, and aesthetic surgery. She holds the ABHRS Diplomate title — the only physician in Croatia and one of 260 physicians worldwide to have earned it — and as a FISHRS she is the only physician from Croatia in regular membership of the ISHRS. In March 2026 she defended her doctoral thesis on the connection between hair transplantation and biopsychosocial factors of health.

So mesotherapy is not performed by someone who gives injections occasionally, but by a physician who works with the scalp every day and ties the composition of the preparation to measured findings. The Polyclinic has been operating since 1998; it was founded by her parents, and today two generations of the family work here. You can have the treatment in Zagreb and in Daruvar, with the same equipment and the same protocol.

Meet the whole team

Ana Maletić, MD, PhD, head of the Hair Center, with a trichoscopic scalp analysis — Ana Maletić, MD, PhD, head of the Hair Center at Polyclinic Maletić

Watch

See what a scalp analysis looks like

TrichoLab Studio: precise scalp diagnostics

Price

Price and the first step

One treatment of individualized scalp mesotherapy costs €150.00, and a series of six treatments €750.00. The trichoscopic scalp analysis costs €135.00, and its findings determine whether we will suggest the therapy at all.

The consultation is free of charge. You come in, we look at the scalp and tell you what we see — including the possibility that mesotherapy makes no sense in your case. You can also see the prices of all treatments in the price list, and arrange an appointment via contact. You will find the other scalp therapies at the Hair Center.

If you have noticed the first signs and are not sure whether to do anything, that is exactly the moment for an examination. In the early phase, the choice of therapies is widest.

Hair loss treatment with individualized scalp mesotherapy (1 treatment)

€150.00
Hair loss treatment with individualized scalp mesotherapy (6 treatments)

€750.00
Trichoscopic scalp analysis (TrichoLAB FotoFinder)

€135.00

See the full price list

Which method for whom

Patients most often ask us which hair therapy is the best — and the answer is that a universally best therapy does not exist. Each person’s hair loss has its own cause, phase, scalp condition, and degree of follicle preservation. That is why the same method gives a good result in one person and does not match the findings in another.

So we build the treatment plan around what is actually measured on your scalp. After the trichoscopic analysis we know what kind of hair loss is involved, how far the process has advanced, and whether there are still follicles with regenerative potential. From those findings comes one therapy, or a combination of methods that complement each other. Sometimes what comes out is that a treatment makes no sense in your case — and then we talk about a transplant or about monitoring, depending on the findings. You will hear that at the first examination, not after several paid treatments.

Below is an overview of the methods we perform, how they differ, and when each one comes into consideration.

Method	How it works	When it comes into consideration
Scalp mesotherapy	Delivers a preparation of vitamins, minerals, and amino acids, composed according to your findings, into the scalp skin to improve the conditions in which the follicle works.	For weakened, thinning hair, early-stage thinning, and increased shedding after childbirth, illness, or a longer period of stress.
PRP treatment	Uses plasma from your own blood and the growth factors it contains, so the treatment involves drawing your blood and preparing it.	For increased shedding and thinning, when the follicles still exist but produce a thinner, weaker hair.
Polynucleotides	Purified DNA fragments that reduce inflammation in the scalp and stimulate the formation of new blood vessels, improving the scalp’s blood supply.	For diffuse thinning and a sensitive scalp, and when you prefer a solution that does not involve drawing blood.
Scalp filler	Delivers a complex of peptides and hyaluronic acid into the scalp skin that acts on the follicle itself. Unlike facial fillers, the goal is not added volume but strengthening the existing hair.	For weakened, thin hair and in the earlier phase of thinning, while the follicles are still active.
Laser hair growth treatment	Uses a medical Er:YAG laser to improve the scalp’s blood supply and encourage follicles to shift from resting into the growth phase, with no needles and no downtime.	For increased shedding and for strengthening existing hair, on its own or alongside other therapies.
Hair transplant	Your own follicles from the donor area are moved to the areas where hair no longer grows.	When certain regions no longer have active follicles, because no treatment can bring back hair that is gone there.

Scalp mesotherapy

How it works

Delivers a preparation of vitamins, minerals, and amino acids, composed according to your findings, into the scalp skin to improve the conditions in which the follicle works.