Since 1998 · Zagreb & Daruvar
Scalp Mesotherapy in Croatia
Hair that has thinned, lost density, and keeps ending up on the brush is usually first fought with shampoos and vitamins. Scalp mesotherapy delivers nutrients directly into the skin of the scalp, where the follicle does its work. Before we suggest a single treatment, a scalp analysis shows whether mesotherapy would help you at all — because for some people it will not.
Mesotherapy is the treatment people often think of at the first signs of hair loss, before significant thinning has occurred. To determine whether it is the best choice in an individual case, we first analyse the scalp and only then agree on a series of treatments.
Is this for me?
What scalp mesotherapy is and what is actually injected
Scalp mesotherapy introduces a preparation of nutrients directly into the scalp skin with very fine needles at shallow depths. The aim is for the substances to reach the layer containing important follicular structures, rather than remaining on the surface or passing through the whole body.
This is a medical procedure, not a cosmetic treatment. That means an examination comes first, and the composition of the preparation is set for each patient individually, not according to a preset scheme.
What goes into the preparation
Scalp mesotherapy preparations most often contain vitamins, minerals, amino acids and other substances that support follicle function and scalp skin condition. We select the composition and quantity individually according to the findings, so two patients of the same age with similar hair may not receive the same preparation.
Mesotherapy improves the conditions in which hair grows.
Why an injection, and not a shampoo or a pill
Most people come to us after several months of ampoules, shampoos, and supplements. The problem with that route is not the ingredients but getting them to where they need to be. Applying them into the skin of the scalp achieves higher local availability of the substances with less exposure for the rest of the body — which is the basis of the method.
That also explains why mesotherapy cannot replace treating the cause. If the body lacks iron or the thyroid is not working as it should, that finding is treated with medication, not with an injection into the scalp.
The right indication
Who benefits most from scalp mesotherapy
People who come when changes are only beginning benefit most. When hair has started thinning but follicles are still alive and active, therapy has something to work with. The further the process has advanced, the less reasonable it is to expect significant improvement.
Situations in which we suggest it
- Weakened and damaged hair — a thin hair shaft that breaks easily and struggles to hold a style.
- Early-stage hair loss — when density is dropping and the part line is slowly widening.
- Hair loss after childbirth, illness, or a longer period of stress — when the condition has settled but recovery is not coming.
- Preserving hair quality — in people whose process is known and predictable, where the goal is to slow it down.
- Maintaining the results of other scalp therapies — when the state that has been achieved needs to be kept.
Mesotherapy, PRP, or polynucleotides — what decides
That question comes up at almost every consultation, because all three therapies target the same scalp condition. They differ in what is applied. A PRP treatment uses your own plasma, polynucleotides are a purified preparation with a regenerative effect, and mesotherapy delivers nutrients composed according to your findings.
The decision is based on scalp condition, established through a detailed examination, rather than treatment popularity. Combining two therapies is common because the same scalp may need both nourishment and regeneration.
“Mesotherapy nourishes the scalp and can improve hair quality, but does not stop hereditary hair loss. If someone comes with advanced androgenetic alopecia, these treatments will not substantially improve scalp condition or change what brought them here. It is important to tell the patient this before therapy begins.” — Ana Maletić, MD, PhD
How it is performed
What a scalp mesotherapy treatment with us looks like
The whole procedure takes about half an hour and is a minimally invasive medical procedure.
- Duration
- about 30 minutes
- Anesthesia
- usually not needed
- Protocol
- most often a series of 6 treatments; the schedule is set by your findings
- Performed by
- Ana Maletić, MD, PhD
1 · Examination and assessment of the scalp and general health. We examine the scalp in detail with a trichoscopic camera to assess the scalp and hair. We also review health status, any illnesses, allergies, medication use and family history of scalp conditions. We then assess whether mesotherapy could have an effect.
2 · Preparation of the solution and scalp. We determine the mesotherapy composition according to the findings. We photograph the scalp and disinfect it according to medical protocol.
3 · Application. We apply the preparation with very fine needles, in a series of points across the area we have mapped out. Anesthesia is usually not needed.
4 · After treatment. You can resume your activities immediately, without resting. We recommend avoiding swimming pools immediately after treatment and washing your hair the following day.
Treatment is usually given as a series of six sessions. Afterwards, we analyse and photograph the scalp again and compare it with the initial findings, allowing progress to be assessed objectively.
See the full price listHonest about the limits
The limits of scalp mesotherapy
The method has four limitations you should know before agreeing to a series.
It does not stop hereditary hair loss. Mesotherapy can strengthen hair, but cannot stop a genetically determined process.
It does not create new follicles. Where a follicle is gone, no preparation brings it back. In that situation, a conversation about a hair transplant is more honest than a series of treatments.
It cannot produce a substantial increase in density. Mesotherapy mainly improves hair quality and increases density, but not substantially. Results are better when it is combined with other therapies than when used alone.
Side effects exist, although they are rare. They are usually mild and temporary: redness, tenderness, itching, swelling or minor bruising. Less common events described in the literature include scalp inflammation and, very rarely, an inflammatory reaction and paradoxically increased hair loss. This is why a physician performs the treatment and an examination comes first.
If your findings show that mesotherapy would change nothing for you, you will hear that at the first examination, together with a proposal that has support in the findings. A series of six treatments takes both time and money, so we suggest it only when there is a reason for it.
After the series
What the result looks like after six treatments
The final result is visible a few weeks after the last treatment, and sometimes after several months. For some patients, the first changes are small: fewer hairs remain on the brush after washing. Hair looks healthier, of better quality and somewhat denser.
Why us
Why choose us for scalp mesotherapy
ABHRS Diplomate
Dr. Ana Maletić is the only physician in Croatia with this title, one of 260 physicians worldwide
The only ISHRS Fellow from Croatia
the most distinguished membership level in the international hair transplantation society
One of 6 clinics worldwide
with this level of international certification for hair treatments
The only clinic in Croatia offering all four hair transplantation methods
FUE, DHI, Sapphire, and STRIP — we choose the method based on your findings, not on what we happen to offer
Since 1996
the start of training in hair transplantation, two years before the Polyclinic opened in 1998
Trichoscopic scalp analysis
a detailed examination providing insight into hair and scalp skin condition
An individually composed preparation
composition and quantity are determined by scalp findings
We also tell you when therapy makes no sense
if your findings show mesotherapy would change nothing for you, we will tell you so
Who we are
Who will be taking care of you
The Hair Center is led by Ana Maletić, MD, PhD, a specialist in plastic, reconstructive, and aesthetic surgery. She holds the ABHRS Diplomate title — the only physician in Croatia and one of 260 physicians worldwide to have earned it — and as a FISHRS she is the only physician from Croatia in regular membership of the ISHRS. In March 2026 she defended her doctoral thesis on the connection between hair transplantation and biopsychosocial factors of health.
The polyclinic has operated since 1998. It was founded by her parents, and two generations of the family work here today. Treatment is available in Zagreb and Daruvar, with the same equipment and protocol.
Meet the whole team
Watch
See what a scalp analysis looks like
Trichoscopic scalp examination, precise scalp diagnostics
Price
Price and the first step
Prices for one treatment of individualized scalp mesotherapy and a series of six treatments are listed in the table below. The price of the trichoscopic scalp analysis is listed in the table below.
You come in, we look at the scalp and tell you what we see — including the possibility that mesotherapy makes no sense in your case. You can also see the prices of all treatments in the price list, and arrange an appointment via contact. You will find the other scalp therapies at the Hair Center.
If you have noticed the first signs and are not sure whether to do anything, that is exactly the moment for an examination. In the early phase, the choice of therapies is widest.
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Hair loss treatment with individualized scalp mesotherapy (1 treatment)
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Hair loss treatment with individualized scalp mesotherapy (6 treatments)
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Trichoscopic scalp analysis (TrichoLAB FotoFinder)
Which method for whom
Patients most often ask us which hair therapy is best. There is no universally best therapy: each person’s hair loss has its own cause, stage, scalp condition and degree of follicle preservation. The same method may therefore work well for one person but not another.
We therefore build the treatment plan around a detailed scalp examination and, when needed, a health assessment. After trichoscopic analysis, we know the type and stage of hair loss and whether follicles with regenerative potential remain. The findings lead to one therapy or a combination of complementary methods. Sometimes they show that treatment makes no sense in your case; we then discuss transplantation or monitoring, depending on the findings. You will hear this at the first examination, not after several paid treatments.
Below is an overview of the methods we perform, how they differ, and when each one comes into consideration.
| Method | How it works | When it comes into consideration |
|---|---|---|
| Scalp mesotherapy | Delivers a preparation of vitamins, minerals and amino acids, composed according to the findings, into the scalp skin. | For weakened, thinning hair, early-stage thinning, and increased shedding after childbirth, illness, or a longer period of stress. |
| PRP treatment | Uses plasma from your own blood and the growth factors it contains, so the treatment involves drawing your blood and preparing it. | For increased shedding and thinning, when the follicles still exist but produce a thinner, weaker hair. |
| Polynucleotides | Purified DNA fragments that reduce inflammation in the scalp and stimulate the formation of new blood vessels, improving the scalp’s blood supply. | For diffuse thinning and a sensitive scalp, and when you prefer a solution that does not involve drawing blood. |
| Scalp filler | Delivers a complex of peptides and hyaluronic acid into the scalp skin that acts on the follicle itself. Unlike facial fillers, the goal is not added volume but strengthening the existing hair. | For weakened, thin hair and in the earlier phase of thinning, while the follicles are still active. |
| Laser hair growth treatment | Uses a medical Er:YAG laser to improve the scalp’s blood supply and encourage follicles to shift from resting into the growth phase, with no needles and no downtime. | For increased shedding and for strengthening existing hair, on its own or alongside other therapies. |
| Hair transplant | Your own follicles are moved from the donor region to areas where hair is absent or thinning. | When certain regions no longer have active follicles, because no treatment can bring back hair that is gone there. |
Scalp mesotherapy
How it works
Delivers a preparation of vitamins, minerals and amino acids, composed according to the findings, into the scalp skin.
When it comes into consideration
For weakened, thinning hair, early-stage thinning, and increased shedding after childbirth, illness, or a longer period of stress.
How it works
Uses plasma from your own blood and the growth factors it contains, so the treatment involves drawing your blood and preparing it.
When it comes into consideration
For increased shedding and thinning, when the follicles still exist but produce a thinner, weaker hair.
How it works
Purified DNA fragments that reduce inflammation in the scalp and stimulate the formation of new blood vessels, improving the scalp’s blood supply.
When it comes into consideration
For diffuse thinning and a sensitive scalp, and when you prefer a solution that does not involve drawing blood.
How it works
Delivers a complex of peptides and hyaluronic acid into the scalp skin that acts on the follicle itself. Unlike facial fillers, the goal is not added volume but strengthening the existing hair.
When it comes into consideration
For weakened, thin hair and in the earlier phase of thinning, while the follicles are still active.
How it works
Uses a medical Er:YAG laser to improve the scalp’s blood supply and encourage follicles to shift from resting into the growth phase, with no needles and no downtime.
When it comes into consideration
For increased shedding and for strengthening existing hair, on its own or alongside other therapies.
How it works
Your own follicles are moved from the donor region to areas where hair is absent or thinning.
When it comes into consideration
When certain regions no longer have active follicles, because no treatment can bring back hair that is gone there.
The methods are often combined, because the same scalp can simultaneously hold weakened follicles and areas where hair no longer grows. Then one method preserves and strengthens what is left, while the other replaces what has been permanently lost.
It is equally important to know what these methods cannot do. No therapy creates new follicles, so where a follicle has been permanently lost, no number of treatments can change the situation; transplantation is indicated. If hair loss is linked to thyroid disease, nutrient deficiency or a hormonal change, that condition is treated separately, with scalp therapy alongside it rather than instead of it.
The right method is the one that suits your scalp condition. Every plan therefore begins with analysis and discussion, followed by treatment selection.
Patient reviews
What our patients say
Reviews taken from our Google Business profiles, Zagreb and Daruvar, translated from Croatian.
★★★★★
“A month ago I had an FUE hair transplant with Dr. Ana Maletić. From the professional side, my hair was done perfectly. I was lucky that my hair did not shed and started growing right away. Dr. Maletić’s expertise is obvious and makes her, without question, the leader in this field in Croatia. But my real satisfaction and gratitude lie in how the Polyclinic treats its patients. They are highly professional, yet approachable and compassionate at the same time. Nurses Matea M. and Valerija left a positive mark on my whole experience and made it more pleasant and calming. To anyone in Croatia looking for a hair transplant, I warmly recommend this Polyclinic. You will get top results and excellent care!”
★★★★★
“I had a hair transplant and I am more than satisfied with this extraordinary, exceptionally professional, life-changing procedure! A big thank you to Dr. Ana, Danijela, Romana, and everyone else who took part in this wonderful experience. My sincerest thanks! Marko S.”
★★★★★
“All praise to the entire staff of the polyclinic. I have already had my second PRP scalp treatment and I can only commend the whole team. I would especially like to praise the doctor for her exceptional expertise, patience, and warm approach. From the first examination to the procedure itself I felt safe and informed. The whole course of treatment was professional and well organized — I received clear and detailed instructions before, during, and after the procedure, which gave me extra confidence. The procedure itself was stress-free, with every step explained along the way, which meant a lot to me. The atmosphere is pleasant and relaxing, and the staff exceptionally kind and helpful. I am very satisfied with the results so far and look forward to further progress. I definitely recommend it to anyone considering a PRP scalp treatment — you are in safe and expert hands!”
★★★★★
“A few years ago I saw Dr. Ana Maletić for a facial hair correction using the FUE method, which made my beard somewhat denser. The results are fantastic — the work was done with such dedication and care. From the first meeting at the polyclinic she radiated confidence and knowledge of her work, along with a readiness and kindness to answer every question I had. All recommendations for Dr. Ana and her entire professional and friendly team.”
★★★★★
“I have been their patient and admirer for years. They have always known how to make my mom and me feel comfortable and welcome. My mom had a neck lift six years ago, and today I came in for PRP for hair growth. I cannot recommend them enough. Thank you, Ana!”
★★★★★
“I am very satisfied with Dr. Maletić’s results, from the beginning to the end of the hair transplant process. Five months after the procedure my hair looks phenomenal. The results I got, considering the number of grafts transplanted, pleasantly surprised me when compared with other clinics outside Croatia. As for the price, there is no big difference compared to clinics abroad, while the quality and expertise are on the level of top clinics. A big plus is that I did not have to travel outside the country, which made the whole process far less stressful for me.”
★★★★★
“I have rarely experienced such a professional, coordinated, and harmonious team. The atmosphere during the hair transplant was so pleasant that they even treated me to the occasional musical number. That relaxed atmosphere made the boredom of the procedure easier to bear. Although I do wonder whether some of you might be better off on a stage than in an operating room. Once again, a big thank you — I am already looking forward to the results in a few months!”
★★★★★
“A great experience, team, and final result. In short, I had an eyebrow transplant. Everything went exactly as Dr. Ana Maletić explained. The whole team was very kind and professional from start to finish, and I am now at peace because I finally have eyebrows. They look very natural, and the density is just as it should be. All recommendations!”
★★★★★
“A more than positive experience at Polyclinic Maletić, both in Zagreb and in Daruvar. I had a hair transplant and I am very satisfied with the approach and the procedure. I recommend it to everyone, especially to women who, like me, lost their hair after an illness. Once again, thank you to the kind team, and especially to Dr. Ana Maletić.”
★★★★★
“I just had a hair transplant. I am satisfied. Well done to Dr. Duško Maletić and the team in Daruvar. They are kind, professional, and do quality work. I recommend them.”
Questions and answers
Frequently asked questions
Does scalp mesotherapy hurt?
You can feel it, but only briefly. We inject the preparation with very fine needles into the superficial scalp skin, using vibration at the injection site to reduce discomfort. Anesthesia is usually unnecessary, and most people describe the treatment as uncomfortable rather than painful.
How many scalp mesotherapy treatments are needed?
A series of six treatments is most common. The number and schedule depend on the scalp findings, as not all types of hair loss respond equally. After the series, we analyse the scalp again before discussing whether further treatment is needed.
When do the results of scalp mesotherapy show?
Not immediately. The hair growth cycle takes months, so changes in hair quality and thickness are assessed only after several months by comparing photographs with the initial condition.
How does mesotherapy differ from a PRP treatment?
PRP uses your own plasma, so it involves drawing blood and preparing it, while mesotherapy applies a preparation of nutrients composed according to your findings. In some patients we combine them, because they complement each other — and which is more suitable for you shows in the scalp analysis.
Does scalp mesotherapy have side effects?
They are usually mild and temporary: redness, tenderness, itching, swelling or minor bruising at the injection site. Less common events described in the literature include scalp inflammation and, very rarely, an inflammatory reaction and paradoxically increased hair loss. This is why a physician performs the treatment in medical conditions after examining the scalp.
Does mesotherapy help with hereditary hair loss?
It can improve scalp condition, but does not stop the hereditary process. In advanced hair loss, treatments alone will not address what brought you here, so an honest discussion about other options is more useful than a series of injections.